Since the victory of the Islamic Revolution in 1979, Iran has considered the Zionist regime as an illegitimate and fake regime. Realizing the anti-Zionist nature of the Iranian Islamic Revolution, the Israelis did not spare any efforts to weaken and destroy the Islamic system. Therefore, the Zionist regime considers Iran an existential, material, and destructive threat for itself. In this context, in recent years, the Zionist regime has launched a campaign of Iran-phobia and pressure on Iran in the international community by emphasizing the threat of Iran's nuclear program. Before the Iran nuclear deal and The P5+1 agreement in 2015, the Zionist regime had adopted various strategies toward Iran, and the challenging question of the current research is what will be the coordinates of the plans of the Zionist regime toward Iran's nuclear program? Will the Zionist regime continue with its previous strategies against Iran, or will it make changes in its strategy against Iran in the framework of the new conditions? The findings of this research show that if before this Zionist regime, the advancement of the scenario of Iran phobia and highlighting the threat of Iran in the international community was secret measures, intensive diplomacy, and the threat of using the military option, from now on, the strategy of this regime in facing Iran is based on the new axes, including establishing its position as the supervisor of Iran's nuclear program, as well as containing Iran by perpetuating civil wars in Iran's spheres of influence, have been redesigned.